check for bowel cancer screening

Check For Bowel Cancer - Screening At Home

Check For Bowel Cancer - At-Home Screening – Quick, Easy, and Doctor-Supported

A quick and easy test to screen for bowel cancer—guided by expert doctors.
Get results and personalised advice on screening.

Get Started Today
cancer genetic dna home test

Check For Bowel Cancer: Screening Saves Lives

Bowel cancer is the 3rd most common cancer in both males and females in the UK. Like most cancer it becomes more common with age, especially after 45. But sadly we are now seeing an increase in ‘early onset’ colorectal cancer, under 50 years of age. Cases under 50 are predicted to double in the next 10 years.

Using at-home testing  can help us diagnose more cancers early, when they are easier to treat.

How It Works

Step 1: Order Your Kit Online

Order your kit online in just a couple of minutes.

Step 2: Sample Kit Delivered

Quick delivery, usually within 3 days, ready to use.

Step 3: Send Your Sample Back

Prepaid return, no hassle.

Step 4: Get Your Results

Receive your results and expert guidance in 5 days.

Why Our Bowel Cancer Screening is Different

Doctor Consultation Included For Positive Results

Unlike competitors, we provide in-depth post-test consultations with our experienced GPs.

Actionable Results

We don’t just test; we help you understand what to do next. We give everyone personalised advice on bowel cancer screening and risk.

More Accurate Testing

Our tests detect blood in the stool at much lower levels than NHS screening.

Plus we can offer testing every year, from 45 years of age which means detecting more cancers early.

Is This Test Right for You?

Do you have a family history of cancer?

Worried about the rise in bowel cancer?

Want to test more often than the NHS screening?

Want to start screening for bowel cancer younger than the NHS screening?

Feel healthy but want to be proactive about your health?

If you can answer yes to any of these questions then this test can help.

Frequently Asked Questions

It is quick and easy to screen for bowel cancer at home using a home test kit. The kit contains a small plastic stick which is used to take a tiny sample of your stool and then placed in a plastic tube. The tube can then be safely returned via a normal post box. The laboratory analyses the sample looking for tiny amount of haemoglobin (red blood cells), which are not visible to the naked eye. 

A positive test result does not mean you have a diagnosis of cancer, but it means you need more checks. The test has shown haemoglobin and this can indicate bleeding from the bowel. Usually a colonoscopy, a camera test to check inside the bowel, is recommended.

A negative test is very reassuring. It means we can be over 99% sure that you don’t have bowel cancer at the time of the test. You should continue to report any symptoms to your GP.

In studies of over 40,000 people they showed testing every year for adults over 45 gave the best results in detecting cancer early.

We only use medical-grade laboratory testing. We use a leading laboratory, who are fully accredited to ISO 15189. This means you can be confident in the accuracy of your results.

We are also unique in that we help you with any positive results. A free GP consultation is included for anyone with a positive result. Our experienced private GPs will be on hand to ensure you get the best possible after care.

We test for a much lower level of blood than the NHS bowel cancer screening programme. The NHS programme only reports if the level is above 120, but we will tell you if your level is above 4.

At-Home Bowel Cancer Screening  – £91

Fees include:

  • Kit delivery and all postage fees.
  • Laboratory analysis.
  • Report via email and personalised advice on screening.
  • GP consultation for any positive results including advice on referrals via NHS or private medical insurance.

The NHS in England currently offers a home test kit for screening to those aged 54 to 74 years of age, every 2 years.

    • If you are registered with an NHS GP it will automatically be sent to your home address.
    • People aged 75 and over can call up to request a test kit.
  • Special risk groups
    • People with a high-risk gene mutation such as Lynch Syndrome will be eligible for NHS screening such as a colonoscopy every 2 years from 25 years of age.
    • People without a known gene mutation but at high risk for instance due to a family history or a previous bowel cancer may also be eligible for extra testing. Check with your doctor to find out if this might apply to you.

If you have symptoms of bowel cancer, talk to your GP about getting a test.

If you have symptoms then we would recommend talking to your GP. We would be happy to see you for a GP consultation online or in-person at Coyne Medical.

Book A GP Consultation

Yes we can offer a full range of health screening from at-home genetic testing to whole body MRI. Check out our packages here.

Pricing and Booking

💰 Price: £91 – Includes Test Kit + Delivery Fees + Laboratory Analysys +Free Follow-Up For Positive Results

📅 Order Your Test Today

Backed by Science & Trusted by Experts

✅ Approved under CQC & UKAS

✅ Partnered with leading regulated laboratories.

As Featured In

Your Health Matters – Get Started Today.

📌 Order Your At-Home Bowel Cancer Screening Test Now

Want to learn more about how to reduce your risk of bowel cancer?

Worried about a family history of bowel cancer?

Read Our Doctor's Guide To Bowel Cancer Risk, Prevention and Early DetectionLearn About Genetic Screening At-Home

We're Here To Help

If you can’t find the appointment you need or need other assistance please get in touch with us and we would be happy to help.

Email us at contact@coynemedical.com or call us on 02077313077.


Genetic cancer screening

Genetic Cancer Screening At Home

At-Home Genetic Cancer Screening – Quick, Easy, and Doctor-Supported

A quick and easy saliva test to uncover your inherited cancer risk—guided by expert doctors. Get results and a personalised health plan.

Get Started Today
cancer genetic dna home test

How It Works

What Screenings Do You Actually Need?
Take the 2-minute health quiz

👉 Start the Screening Quiz

Step 1: Video Consultation with a Doctor

Speak with a doctor in 30 minutes.

Step 2: Sample Kit Delivered

Next-day delivery, ready to use.

Step 3: Send Your Sample Back

Prepaid return, no hassle.

Step 4: Get Your Results

Receive expert guidance in 15-20 days.

More Than Just a Test

From interpretation to action—your GP is with you throughout.

State-of-the-art sequencing for accurate, clinically validated results.

Not just testing—continued care, expert monitoring, and personalised support whenever you need it.

Book Your Genetic Screening Today

Is This Test Right for You?

  • Do you have a family history of cancer? → Find out if you’re at risk and take proactive steps.
  • Are you health-conscious? → Get science-backed insights tailored to your DNA.
  • Want a personalised prevention plan? → Our doctors create custom recommendations just for you.

How Genetic Testing Changed Dr Lucy's Life

“Testing helped me reduce my risk of breast cancer by over 95%.”

Frequently Asked Questions

Genes are small sections of DNA that provide the instructions that give us our individual characteristics. Our genes determine the colour of our eyes and hair, our height and other physical characteristics. Genetic testing looks at variations in these genes that determine whether you might be predisposed to certain diseases. Genetic testing can also tell us how your body might respond to drugs. 

The Association of British insurers and the British Medical Association have agreed on a set of questions that insurers can ask your GP when you apply for life insurance. Your GP will be asked about any medical condition that you have suffered in the past or are currently experiencing that may reduce your life expectancy. They are also allowed to ask you and your GP about your family history. They are not allowed to ask or request the results of any predictive genetic testing

Currently, the only exception in the UK to this is if you are applying for insurance with the only exception being if you are applying for life insurance over £500,000 and you have had a predictive genetic test for Huntington’s Disease. Only in this circumstance do you need to tell the insurance company the result of the test, if they ask.

If you have a strong family history of breast cancer for example and you test negative for genes related to this it may be in your interest to disclose this and you may choose to do this. You can read more about the code of the Association of British Insurers here.

There are two possible outcomes from our cancer gene testing: Negative and positive.

If the result is negative it means that the test did not pick up any genes that increase the risk of disease. It doesn’t mean that you will never develop one of the conditions tested for, as there are many other factors aside from genes that can contribute to developing a disease. As we learn more about genetics and disease, it may be that your test results in the future will be updated to reflect new medical information. If this is the case, we will inform you immediately. 

A positive result means you have discovered a gene variant that increases the risk of you developing a certain cancer. You will then be able to work with your doctor to determine what the next steps are for you. This may include options to prevent disease or increased surveillance to detect the disease at an earlier, more treatable stage. 

We ensure the highest level of security for your personal information. We will never sell or share your medical information or data. Full details of our privacy policy are available here. We use our patient portal to securely share copies of your results by email. We can use an alternative method of communication if you wish – just let us know.

The genetic testing laboratory receive your personal information and abide by the extremely strict rules on privacy of sensitive data. You must consent to their receiving and sharing your personal information and data. You may choose to opt-out of anonymised research studies.

We only use medical-grade genetic testing. We use a leading specialist laboratories, who are fully accredited to ISO 15189 and 17025.

Our genetic testing uses both full-gene sequencing and deletion/duplication analysis using next-generation sequencing technology (NGS). This is the most accurate method. Some online DNA testing and family history companies use other methods such ‘genotyping’; this leads to more common false positive and negative results. They can be fun and quick to use but are not meant to guide medical decisions or healthcare.

51 cancer gene screening PLUS pharmacogenomics  – £1300

31 cancer gene screening – £900

Fees include pre test consultation with the doctor, review of medical and family history, and sample taking. Laboratory analysis. Full report and advice on further screening or risk reduction for any positive cancer risk genes.  Detailed report on your pharmacogenetics including advice on medications, dosages, side effects and alternatives.

Follow-up consultation with the doctor at our clinic to discuss your results. Including advice on further referrals and any other health screening indications.

Tumour genes include those related to:

Breast cancer

Ovarian cancer

Uterine cancer

Colorectal cancer

Cutaneous melanoma

Gastric cancer

Pancreatic cancer

Prostate cancer

Renal cell cancer

Thyroid cancer

Full List of Genes Tested

APC, ATM, BAP1, BARD1, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A, CHEK2, EPCAM, HOXB13, MLH1, MSH2, MSH6, MUTYH, NF1, NTHL1, PALB2, PMS2, POLD1, POLE, PTEN, RAD51C, RAD51D, SMAD4, STK11, TP53, VHL

Yes we believe genetic screening is a really powerful addition to our health screening. Check out our packages here.

Pricing and Booking

💰 Price: £900 – Includes Video Consultation + Test + Free Follow-Up

📅 Book Your Test Today

Invest in your health with our doctor-led genetic screening. No hidden fees, no confusion—just expert guidance and actionable insights.

Backed by Science & Trusted by Experts

✅ Approved under CQC & UKAS

✅ Partnered with leading genetic labs

As Featured In

Take Control of Your Future Health

Begin your personalised journey to cancer prevention.
In-clinic and at-home options available

📌 Book Your At-Home Genetic Test Now

Need Help Choosing the Right Test?

Speak to one of our expert doctors

in a 30-minute discovery call.

💳 £250 – Fully refundable if you go ahead with any screening

Book a Discovery Call

We're Here To Help

If you can’t find the appointment you need or need other assistance please get in touch with us and we would be happy to help.

Email us at contact@coynemedical.com or call us on 02077313077.


multi cancer blood test early detection

Multi Cancer Early Detection Blood Test

Why Choose Trucheck™ Intelli Cancer Blood Test?

Detects 70+ cancers

Simple blood test

Quick results in 2 weeks

Early Detection

Your Screening Journey

Step 1: Consultation

  • Schedule online or by phone.
  • Have a consultation with a doctor to review your medical history.
  • Ask any questions about accuracy, benefits, or limitations.

Step 2: Blood Sample Collection

  • A simple blood draw is done at the clinic.
  • Quick and minimally invasive—takes just a few minutes.
  • No special preparation needed.

Step 3: Advanced Lab Analysis

  • Your sample is analyzed using advanced cancer detection technology.
  • Results are ready in 20 days.
  • You’ll receive your results via email, secure portal, or in-person consultation.

Step 4: Doctor Consultation & Next Steps

  • A doctor explains your results and answers any questions.
  • If needed, they’ll guide you on further tests or specialist referrals.
  • If results are clear, you’ll get expert advice on prevention and health monitoring.

Get peace of mind with our health screening packages.

The Multi Cancer Early Detection Blood Test can be added to any of our health screening packages or taken as a standalone test. For a comprehensive review of your health, consider our Ultimate Health Screening package, which combines advanced tests with personalised care to help you stay ahead of potential risks.

Find Out More

What Screenings Do You Actually Need?
Take the 2-minute health quiz

👉 Start the Screening Quiz

How Does the Trucheck™ Intelli Cancer Blood Test Work?

At Coyne Medical in London, we offer the Trucheck™ Intelli multi-cancer blood test, an advanced screening tool that can detect over 70 types of cancer at an early stage.

Cancerous tumours release tiny circulating tumour cells (CTCs) and fragments into the bloodstream. These cells play a key role in cancer spread, especially when they travel in clusters.

The Trucheck™ Intelli test identifies these CTCs in your blood sample, helping to pinpoint the likely organ of origin. If cancer-related cells are detected, your doctor can recommend targeted follow-up tests for further evaluation.

Our Fulham-based clinic provides this cutting-edge blood test as part of a comprehensive health screening or as a standalone service for proactive cancer detection in London.

Frequently Asked Questions

It’s a simple, non-invasive blood test that screens for over 70 types of cancer. It can detect cancer early, even in hard-to-screen areas, and identify the likely organ of origin for precise follow-up.

This test is ideal for adults at higher risk of cancer due to age, family history, or lifestyle factors. It’s also valuable for those seeking peace of mind.

  • Aged 40 years of age or older
  • Aged 35 to 39 years of age only if one of the following apply:
    • a family history of cancer
    • known to have an inherited cancer gene mutation e.g. BRCA1
    • obesity with a BMI over 30
    • type 2 diabetes
    • history of infectious disease linked to cancer e.g. hepatitis B or C
    • history of exposure to cancer causing chemical e.g. through work

The test has been validated in clinical trials, showing high sensitivity and specificity for cancer detection, especially for aggressive cancers.

  • Trucheck™ Intelli is a blood test that can detect more than 70 types of early-stage cancer in people without any symptoms.
    • The sensitivity is 88.2% – meaning that for every 100 patients tested who have cancer, it will correctly identify 88 of those patients, resulting in a 12% false negative rate.
    • The specificity is 96% – meaning that for every 100 people tested, that do not have cancer, Trucheck ™ Intelli will correctly identify 96 of these individuals, resulting in a 4% false positive rate.
    • False positives occur in all screening tests, the 4% level in Trucheck tests compares very favourably with other cancer screening such as PSA testing (75%), FIT testing (25%) and mammograms (7-12% at first mammogram) which all have much higher false positive rates.

If a cancer signal is detected, your results will include the likely organ of origin. This will help to decide on what tests to do next, remember that a positive result means a high risk of cancer but it is not confirmed. Your doctor will guide you on the next steps, which may include further tests or specialist referrals.

Results are typically available within two weeks. Your doctor will contact you as soon as they are ready.

No, this test is a complement to routine screenings like mammograms or colonoscopies, not a replacement. It helps detect cancers that lack routine screening methods.

The Trucheck™ Intelli can detect over 70 types of cancer. Including the most common cancers; breast, bowel, prostate, ovarian, and lung cancers (see full list below).

Trucheck™ cannot detect blood or lymphatic system cancers because CTCs are associated with solid organ malignancies.

  • Adenocarcinoma ( Salivary Duct, Thyroid, Breast, lung, Oesophagus, Stomach, Duodenum,
    Jejunum, Ileum, Colon, Rectum, Pancreas, Gallbladder, Bile Duct, Liver, Ovary, Prostate, Uterus);
  • Squamous Cell Carcinoma (SCC; Buccal Mucosa, Hard Palate, Larynx, Lip, Oral Cavity, Paranasal Sinus, Pharynx, Pyriform Fossa, Retromolar Trigone, Soft palate, Tongue, Tonsil, Oesophagus, Lung, Penis, Cervix, Vulva, Vagina, Anorectal, Skin);
  • Adenosquamous Carcinoma (Oesophagus, Lung);
  • Neuroendocrine (Lung, Esophagus, Duodenum, Jejunum, lleum, Thymus, Adrenal, Pancreas, Prostate, Colon, Rectum);
  • Renal Cell Carcinoma (Kidney);
  • Transitional Cell Carcinoma (Bladder, Renal Pelvis, Ureter);
  • Gastrointestinal Stromal tumors (Stomach, Duodenum, lleum, Jejunum, Colon, Rectum);
  • Melanomas (Cutaneous, Mucosal);
  • Mesothelioma (Plural, Peritoneal);
  • Sarcomas (Carcinosarcoma, Chondrosarcoma, Leiomyosarcoma, Osteosarcoma, Liposarcoma);
  • Small Cell Lung Cancer (Lung);
  • Glioma.

No. The test is designed for people without symptoms. If you have symptoms, you should seek urgent medical advice.

In the future, the tests may be used to help guide which patients with symptoms need further checks such as a biopsy but this is still at a research stage.

In studies, the test is positive in both early and late-stage cancers. This is good because many current tests only detect cancers when they are at an advanced or late stage. Early diagnosis is likely to make treatment more successful.

No. It is only suitable for people who have not had cancer.

There are other similar tests available to monitor patients after cancer treatment. We would recommend you speak with your treating doctor or surgeon to see if there is a test suitable for you.

It can be a useful addition to your yearly health screening or medical check-up. You should discuss this with your Doctor how often or when is the right time for you to test.

If you have more questions about the test itself then the laboratory has lots of detailed scientific information available here.

Take control of your health today. Book your cancer screening with Coyne Medical

Book Now and Take Control of Your Health

Not sure which screening is right for you?

Book a 30-minute Discovery Call with our expert doctors – £250 (refundable against any health screen).

Why Patients Choose Us

best gp in fulham

As Featured In

We're Here To Help

If you can’t find the appointment you need or need other assistance please get in touch with us and we would be happy to help.

Email us at contact@coynemedical.com or call us on 02077313077.


Genetic cancer screening

Genetic Screening London – Coyne Medical

Take Control with Genetic Screening for Inherited Cancer Risk

Dr. Lucy’s story shows how personalised testing can help you act early.

Our Co-Founder, Dr. Lucy, was researching genetic screening for her patients when she discovered her own gene mutation. With a breast cancer risk of over 60%, she chose a risk-reducing mastectomy, lowering her risk to less than 5%. Now, she’s passionate about giving you the same opportunity to take control of your health and prevent cancer.

The Most Common Inherited Cancers—and How We Can Help You Stay Ahead

These five types of cancer are most commonly linked to inherited genetic mutations. Here’s how genetic screening can reveal your risk and how we support you in acting on it.

🧬 Genes We Test

  • MLH1, MSH2, MSH6, PMS2 (Lynch syndrome)

  • APC (Familial Adenomatous Polyposis)

  • MUTYH

Gene mutations cause about 35% of early-onset colorectal cancer, when people get cancer under 50 years of age.

📈 Risk Increase

  • Lynch syndrome: Bowel cancer risk ranges from 12% to 75% before 75 years of age.

  • Familial adenomatous polyposis (FAP): This is caused by a mutation in an APC gene. Polyps start in childhood, up to 90% of people will develop cancer by 45 years of age without treatment. Some types of APC gene mutation cause a milder form of FAP, these people have fewer polyps and develop cancer at older ages, on average 54 years.

  • MUTYH-associated polyposis (MAP): Caused by mutations in the MUTYH gene. Usually, people are only affected if they inherit TWO faulty copies of the MUTYH gene. Occasionally some people have a combination of mutations in MUTYH and APC genes. The risk of bowel cancer in patients with two MUTYH gene mutations has been estimated at between 43%  to 100%. People with only one faulty copy may also be at slightly increased risk.

  • Other less common gene mutations include POLE and POLD1MSH3, and NTHL.

🛡️ If You Test Positive

  • Early Detection
    • Colonoscopy: For example for MLH1 mutation carriers bowel cancer screening by a colonoscopy is recommended every 2 years from 25 years of age. This will help to detect cancers earlier, when treatment is easier and more successful.
  • Prevention
    • Aspirin: Taking a simple aspirin tablet daily for 2 years reduced the risk of bowel cancer by 60%. That’s an enormous benefit for a simple medicine and a great example of why it is so important we find more people with these mutations so they get to actually prevent their cancers.
    • Fibre: a high-fibre diet can also reduce the risk of other cancers associated with Lynch Syndrome such as stomach and endometrium (womb).
    • Other Cancers: you can discuss options for reducing risk of other cancers. For instance, many women with Lynch Syndrome choose to have a hysterectomy (removal of the womb) to reduce the risk of endometrial (womb) cancer, after completing their family in their mid to late 40’s.

🧬 Genes We Test

  • BRCA1 and BRCA2

  • PALB2, TP53, CHEK2, ATM

  • CDH1, PTEN, STK11

About 5-10% of breast cancers are directly caused by an inherited genetic mutation. This means the person has inherited a ‘fault’ in a gene. linked to breast cancer risk from either their biological mother or father.  

📈 Risk Increase

  • BRCA1 & BRCA2 – High risk:  these cause a high risk of breast cancer, for example people with a BRCA1 mutation may have up to 90% lifetime risk of breast cancer. 
  • PALB2, TP53, CHEK2, ATM – Moderate risk: mutations in these genes carry a 15-60% lifetime risk of breast cancer. The exact estimate will depend on the mutation, as well as other lifestyle factors. 
  • CDH1, PTEN, STK11 – These are much rarer gene mutations which are associated with breast cancer risk.

🛡️ If You Test Positive

  • Annual breast MRI from an earlier age, usually from 30 years of age for females.

  • Risk-reducing medication

    • Medication can reduce the risk of cancer developing by up to 50%
  • Consideration of preventative surgery (mastectomy)

    • Risk-reducing mastectomy and reconstruction can reduce breast cancer risk by over 95%.
  • Protecting Other Family Members

    • It can be a great gift to safeguard the health of your family members by sharing your results. Giving them the power to prevent cancer and detect it earlier. Many of the genes are also linked to other cancers, which we can do additional screening and prevention for, including:
      • Ovarian Cancer
      • Pancreatic Cancer
      • Melanoma

Mutations in Men and Other Cancers

Half of the people with a BRCA1 or BRCA2 mutation, will be biological males. Many men don’t worry about a family history of breast cancer but this is a mistake.

  • Breast Cancer: Men with a BRCA1 or BRCA2 mutation have an increased risk of male breast cancer
    • It Is important they regularly check their chest and report any changes or lumps.
    • Male breast cancer is generally rare, affecting less than 0.02% of men, if they have a BRCA1 or 2 mutation that jumps to 7-9%.
      • It is strongly recommended that any male who has breast cancer themselves have genetic testing.
  • Prostate Cancer: They have an up to 60% chance of getting prostate cancer in their lifetime. That’s over 8 times the average male.
    • Regular screening such as PSA tests can help them detect this earlier.
    • We also have newer screening options available at Coyne Medical, including the Stockholm3 test.
  • Pancreatic Cancer:  The risk of this cancer particularly affects men over 50 years.
    • Men with a BRCA1 or BRCA2 mutation have over 7 times the risk of an average male.
  • Melanoma skin cancer
    • Regular skin checks and preventative measures are important.

🧬 Genes We Test

  • BRCA1 and BRCA2

  • PALB2, HOXB13, ATM, CHEK2

  • EPCAM, MLH1, MSH2, MSH6

Prostate cancer has a strong genetic component. For example, we know if a man has a brother with prostate cancer they have a 30% chance of developing prostate cancer before 75 years of age. Testing for inherited cancer risk is especially important if there is a family history of prostate cancer before 60 years of age or metastatic prostate cancer.

📈 Risk Increase

  • BRCA2: BRCA2 mutation carriers have up to 8 times higher risk compared to non-carriers. The risk in BRCA1 mutation carriers is lower.

  • HOXB13: increased risk especially with family history, may cause a 3 to 4 times higher chance of prostate cancer.

  • ATM and CHEK2: carriers of these mutations have approximately 2 to 3 times the risk of prostate cancer.

  • Lynch syndrome (EPCAM, MLH1, MSH2, MSH6): Have about 2 times the risk of a non-carrier, but those with a MSH2 mutation may be at higher risk, approximately 23% chance before 75 years of age.

  • PALB2: The risk of prostate cancer is not clear, but regular checks are sensible as some men may be at risk, especially if there is a family history.

🛡️ If You Test Positive

  • Earlier and more frequent PSA testing (prostate cancer blood test)

  • MRI prostate screening

    • Especially valuable for increases in PSA and more accurate diagnosis.
  • Personalised decisions around biopsy and treatment

  • Protecting Family Members

    • Relatives can benefit from extra and earlier prostate cancer screening. Many of the genes involved are also linked to other cancers, so we can offer extra screening and early detection for these too.
      • Breast Cancer
      • Ovarian Cancer
      • Colon Cancer
      • Pancreatic Cancer

🧬 Genes We Test For

  • BRCA1, BRCA2, PALB2 

  • RAD51C, RAD51D, BRIP1

  • Lynch Syndrome (MLH1, MSH2, MSH6, PMS2 genes)

📈 Risk Increase

  • BRCA1 carriers have approximately a 40% risk.

  • BRCA2 carriers have approximately a 15% risk.

  • Lynch Syndrome (MLH1, MSH2, MSH6, PMS2 genes): the ovarian cancer risk may be up to 13%, in MSH2 carriers.

  • PALB2: the risk is estimated at around 5%.
  • BRIP1: the lifetime risk is about 5.8%.

  • RAD51C and RAD51D the risk is 5.2% and 12% respectively over the person’s lifetime.

🛡️ If You Test Positive

  • Consider preventative surgery after childbearing (salpingo-oophorectomy)

    • Removal of the tubes and ovaries, usually done as a laparoscopic (keyhole) surgery can significantly reduce the risk of cancer
  • Personalised screening

  • Symptom Awareness
    • Ovarian cancer symptoms are often confused for other conditions, such as digestion issues or bladder problems. Knowing you are at increased risk means we can act early on any symptoms.
  • Hormonal and lifestyle support post-surgery

    • We can personalise your management after risk-reducing surgery, including using Hormone Replacement Therapy.
  • Protect Family Members

    • Give the power of prevention and early detection to your loved ones. Many of the genes linked to ovarian cancer are also linked to other cancers which can be preventable and detected earlier with the right screening, including:
      • Breast Cancer
      • Prostate Cancer
      • Pancreatic Cancer
      • Bowel Cancer
      • Endometrial (womb) Cancer

🧬 Genes We Test

  • CDKN2A (most common)

  • BAP1 (associated with multiple cancers)

  • CDK4, PTEN, BRCA2

Melanoma risk is largely inherited as we inherit our skin colour from biological parents, and we know light-skinned people have 2 times the risk of dark-skinned people. But some families do carry a harmful genetic variant which passes on a high risk of melanoma, it is especially worth screening when people have had multiple melanomas, or been diagnosed under 40 years of age.

📈 Risk Increase

  • CDKN2A: 30–70% lifetime risk depending on family history and sun exposure

  • BAP1: linked to melanoma of the skin and eye

  • CDK4: may have a lifetime risk of up to 80% for melanoma

🛡️ If You Test Positive

  • Full skin checks annually

    • We know early detection of melanoma is very important to make treatment easier and more successful.
  • Personalised advice on UV protection and mole surveillance

    • Monthly self-checks are sensible alongside your regular visits. Plus careful UV protection can significantly reduce your risk of melanoma.
  • Early biopsy of suspicious lesions

    • Knowledge of your risk means you can get new lesions checked promptly.
  • Protecting Family Members

    • Knowledge of a gene mutation in a family means you can give your loved the power to prevent cancer and detect it earlier. Many of the genes linked to melanoma are also linked to other cancers, which we can do additional screening and early detection for, including:
      • Pancreatic Cancer
      • Breast Cancer
      • Ovarian Cancer

What Screenings Do You Actually Need?
Take the 2-minute health quiz

👉 Start the Screening Quiz

Know Your Inherited Cancer Risk: Turn Genetic Testing Into Lifesaving Action

At Coyne Medical, we guide you through the process with clarity, compassion, and world-class care. Whether you're assessing cancer risk or exploring how your genes affect medication response (pharmacogenomics).

Early Detection

Identify health risks before they become problems, not after a cancer diagnosis.

Targeted Prevention

Results give you the power to take action to prevent cancer.

Personalised Treatment

Harness the power of your DNA to tailor medications that work best for you.

Your Family’s Future Health

Your results may hold answers for your family too—help protect their future with shared knowledge.

Book Your Genetic Screening Today

More Than Just a Test

From interpretation to action—your GP is with you throughout.

State-of-the-art sequencing for accurate, clinically validated results.

Not just testing—continued care, expert monitoring, and personalised support whenever you need it.

Book Your Genetic Screening Today

Your Genetic Screening Journey: What To Expect

Step 1: Consultation with Your Doctor

Discuss your health and family history with our doctors. We’ll explain the test and answer your questions.

Step 2: Sample Collection

At your clinic appointment you can choose a saliva sample for our 31-gene test or a blood sample for our 54-gene and pharmacogenomics test.

At-Home Testing uses an easy and simple saliva sample, delivered the next day ready to use and return.

Step 3: Results Review

Review your results with your doctor. Together, you’ll create a personalised prevention or treatment plan.

Step 4: Ongoing Care and Long-Term Support

Get long-term support, including regular follow-ups, additional screenings, and guidance for managing health risks.

Choose The Right Genetic Screening For You

Genetic Screening is included in our Ultimate Health Screening package for a truly comprehensive approach to your health. You can also add it to any of our other health screening packages or choose it as a standalone test, tailored to your needs.

Find Out More About Our Health Screening Packages

Option 1: 31-Gene Cancer Screen

  • Ideal For:
    • Individuals taking charge of their future health through knowledge of inherited cancer risk
    • Anyone with a family history of cancer who wants clarity, control, and peace of mind
    • Those ready to take the first step in personalised cancer prevention
  • What’s Included:
    • Tests 31 key genes linked to common cancers
    • Saliva sample
    • Includes consultations, lab analysis, and a follow-up plan

Fee: £900

Book the 31 Cancer Gene Test - In ClinicBook the 31 Cancer Gene Test - At Home

Option 2: 54-Gene Cancer + Pharmacogenomic Screen

  • Ideal For:
    • Individuals seeking the most advanced insights to personalise both cancer prevention and treatment
    • Those who want to understand how their genes affect their health and how medications work uniquely for them
    • People ready to future-proof their health with precision and confidence
  • What’s Included:
    • Tests 54 cancer-related genes
    • Includes 22 genes for how your body responds to medications
    • Blood sample
    • Includes consultations, lab analysis, and a follow-up plan

Fee: £1300

Book the 54 Cancer Gene and Pharmacogenomics Test

Why We're So Passionate About Genetic Screening

Up to 95% of people with Lynch syndrome—a condition that significantly increases the risk of colon, endometrial, and other cancers—remain undiagnosed. That’s not just a statistic. It means thousands of families miss the chance to take action early. Sadly the same statistics apply to the other most common inherited cancer genes like BRCA1 and BRCA2.

At Coyne Medical, this is why Dr Lucy and our team are deeply committed to raising awareness and improving access to genetic screening. We believe that identifying inherited cancer risk shouldn’t be rare—it should be routine. Because when people know their risk, they can protect their future and their families.

Book Your Genetic Screening Today
inherited breast cancer risk brca

Understanding Pharmacogenomics

Your DNA, Your Medicine: The Power of Pharmacogenomics

Pharmacogenomics analyzes how your DNA influences your response to medications, helping your doctor choose the right drug at the right dose for you.

  • Analyze 22 genes that predict your response to common medications.
  • Covers anti-depressants, painkillers, cholesterol-lowering drugs, cardiac medications, and more.
  • Helps reduce the risk of side effects and ensures the medication you take is as effective as possible.

Did you know? 20% of new prescriptions in the UK could be changed if doctors knew a patient’s pharmacogenomics results in advance.

  • Your results don’t just guide your current prescriptions—they provide valuable insights for the rest of your life.

Optimise Your Medications with Pharmacogenomic Testing

Book Your Genetic Screening Today

Take Control of Your Future Health

Begin your personalised journey to cancer prevention.
In-clinic and at-home options available

Book Your Genetic Screening Now

Need Help Choosing the Right Test?

Speak to one of our expert doctors

in a 30-minute discovery call.

💳 £250 – Fully refundable if you go ahead with any screening

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Frequently Asked Questions

Genes are small sections of DNA that provide the instructions that give us our individual characteristics. Our genes determine the colour of our eyes and hair, our height and other physical characteristics. Genetic testing looks at variations in these genes that determine whether you might be predisposed to certain diseases. Genetic testing can also tell us how your body might respond to drugs. 

Our genetic screening tests over 70 gene variants that can predispose to cancer and tell us about how your body reacts to drugs. Importantly, all of these gene variants can be acted upon to help prevent or reduce the risk of the condition. Or for the pharmacogenetic genes can help guide drug treatment either now or in the future. 

Providing a DNA sample is very simple. 

The sample depends on the test chosen.

51 cancer gene screening PLUS pharmacogenomics uses a normal blood sample.

31 cancer gene screening uses a saliva test. The saliva test can be taken at home or in clinic you simply spit into the tube.

We work with two specialist genetic testing laboratories who both registered and highly respected for specialist genetic testing. The laboratories uses the highest standard of genetic testing called NGS (next generation sequencing). This is the most accurate method. Some online DNA testing and family history companies use other methods such ‘genotyping’; this leads to more common false positive and negative results. They can be fun and quick to use but are not meant to guide medical decisions or healthcare.

We expect your laboratory report to be available within 6 weeks of your appointment. This timeframe ensures the highest accuracy and reliability from our trusted labs. We will contact you when it is available to arrange a follow-up consultation. 

The Association of British insurers and the British Medical Association have agreed on a set of questions that insurers can ask your GP when you apply for life insurance. Your GP will be asked about any medical condition that you have suffered in the past or are currently experiencing that may reduce your life expectancy. They are also allowed to ask you and your GP about your family history. They are not allowed to ask or request the results of any predictive genetic testing

Currently, the only exception in the UK to this is if you are applying for insurance with the only exception being if you are applying for life insurance over £500,000 and you have had a predictive genetic test for Huntington’s Disease. Only in this circumstance do you need to tell the insurance company the result of the test, if they ask.

If you have a strong family history of breast cancer for example and you test negative for genes related to this it may be in your interest to disclose this and you may choose to do this. You can read more about the code of the Association of British Insurers here.

There are two possible outcomes from our cancer gene testing:

Negative and positive.

If the result is negative it means that the test did not pick up any genes that increase the risk of disease. It doesn’t mean that you will never develop one of the conditions tested for, as there are many other factors aside from genes that can contribute to developing a disease. As we learn more about genetics and disease, it may be that your test results in the future will be updated to reflect new medical information. If this is the case, we will inform you immediately. 

A positive result means you have discovered a gene variant that increases the risk of you developing a certain cancer. You will then be able to work with your doctor to determine what the next steps are for you. This may include options to prevent disease or increased surveillance to detect the disease at an earlier, more treatable stage. 

Your pharmacogenetic testing will likely show several different variants, in your report there will be detailed recommendations on medications. This might include advice to reduce doses or consider alternative medicines for common drugs such as cholesterol medicines, pain killers and antidepressants.

We ensure the highest level of security for your personal information. Full details of our privacy policy are available here. We use our patient portal to securely share copies of your results by email. We can use an alternative method of communication if you wish – just let us know.

The genetic testing laboratory receive your personal information and abide by the extremely strict rules on privacy of sensitive data. You must consent to their receiving and sharing your personal information and data. You may choose to opt-out of anonymised research studies.

We only use medical-grade genetic testing. We use a leading specialist laboratories, who are fully accredited to ISO 15189 and 17025.

Our genetic testing uses both full-gene sequencing and deletion/duplication analysis using next-generation sequencing technology (NGS). This is the most accurate method. Some online DNA testing and family history companies use other methods such ‘genotyping’; this leads to more common false positive and negative results. They can be fun and quick to use but are not meant to guide medical decisions or healthcare.

51 cancer gene screening PLUS pharmacogenomics  – £1300

31 cancer gene screening – £900

Fees include pre test consultation with the doctor, review of medical and family history, and sample taking. Laboratory analysis. Full report and advice on further screening or risk reduction for any positive cancer risk genes.  Detailed report on your pharmacogenetics including advice on medications, dosages, side effects and alternatives.

Follow-up consultation with the doctor at our clinic to discuss your results. Including advice on further referrals and any other health screening indications.

Yes we believe genetic screening is a really powerful addition to our health screening. Check out our packages here.

Can I see a list of which genes will be tested?

Tumour genes include those related to:

Breast cancer

Ovarian cancer

Uterine cancer

Colorectal cancer

Cutaneous melanoma

Gastric cancer

Pancreatic cancer

Prostate cancer

Renal cell cancer

Thyroid cancer

Full List of Genes Tested

APC CDH1 MLH1 POLD1 SDHB TSC2
ATM CDKN2A MSH2 POLE SDHC VHL
AXIN2 CHEK2 MSH6 PTCH1 SDHD WT1
BAP1 DICER1 MUTYH PTEN SMAD4
BARD1 EPCAM NBN RAD51C SMARCA4
BMPR1A FH NF1 RAD51D SMARCB1
BRCA1 FLCN NF2 RB1 STK11
BRCA2 KIT PALB2 RET TMEM127
BRIP1 MEN1 PDGFRA SDHA TP53
CDC73 MET PMS2 SDHAF2 TSC1

Tumour genes include those related to:

Breast cancer

Ovarian cancer

Uterine cancer

Colorectal cancer

Cutaneous melanoma

Gastric cancer

Pancreatic cancer

Prostate cancer

Renal cell cancer

Thyroid cancer

Full List of Genes Tested

APC, ATM, BAP1, BARD1, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A, CHEK2, EPCAM, HOXB13, MLH1, MSH2, MSH6, MUTYH, NF1, NTHL1, PALB2, PMS2, POLD1, POLE, PTEN, RAD51C, RAD51D, SMAD4, STK11, TP53, VHL

Tumour genes include those related to:

Breast cancer

Ovarian cancer

Uterine cancer

Colorectal cancer

Cutaneous melanoma

Gastric cancer

Pancreatic cancer

Prostate cancer

Renal cell cancer

Thyroid cancer

Full List of Genes Tested

APC CDH1 MLH1 POLD1 SDHB TSC2
ATM CDKN2A MSH2 POLE SDHC VHL
AXIN2 CHEK2 MSH6 PTCH1 SDHD WT1
BAP1 DICER1 MUTYH PTEN SMAD4
BARD1 EPCAM NBN RAD51C SMARCA4
BMPR1A FH NF1 RAD51D SMARCB1
BRCA1 FLCN NF2 RB1 STK11
BRCA2 KIT PALB2 RET TMEM127
BRIP1 MEN1 PDGFRA SDHA TP53
CDC73 MET PMS2 SDHAF2 TSC1

Pharmacogenetics illustrates how genetic changes can affect the influence of drugs. Genetic changes in the proteins responsible for absorption, distribution, metabolism, and excretion of drugs can have a huge impact on their effectiveness and compatibility. Some drugs have different effects on different people, e.g. antidepressants, analgesics, neuroleptics, chemotherapeutics, AIDS medication, thrombosis medication, anaesthetics, beta-blockers, and statins. Reduced or missing activity of a specific enzyme may increase the drug dosage and cause unwanted side effects. On the other hand, a medication that is activated by metabolism may not work if an enzyme is inactive. Enhanced enzyme activity can also affect the response to medication, e.g. by degrading the active ingredients.

Full List of Genes

ABCG2 CYP2D6 G6PD NUDT15 UGT1A1
CACNA1S CYP3A4 HLA-A POR VKORC1
CYP2B6 CYP3A5 HLA-B RYR1
CYP2C19 CYP4F2 IFNL3 SLCO1B1
CYP2C9 DPYD MT-RNR1 TPMT

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If you can’t find the appointment you need please get in touch with us and we would be happy to help.

Email us at contact@coynemedical.com or call us on 02077313077.

Stay Healthy with the Power of Genetic Screening
Book Your Genetic Screening Today – Take Control of Your Health Now!